Bedaquiline fumarate

CAS No. 845533-86-0

Bedaquiline fumarate ( R403323;TMC207 fumarate;R207910 fumarate )

Catalog No. M16140 CAS No. 845533-86-0

Bedaquiline fumarate (R403323, TMC207 fumarate, R207910 fumarate) is a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 42 Get Quote
10MG 65 Get Quote
25MG 102 Get Quote
50MG 140 Get Quote
100MG 178 Get Quote
200MG 267 Get Quote
500MG 464 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Bedaquiline fumarate
  • Note
    Research use only, not for human use.
  • Brief Description
    Bedaquiline fumarate (R403323, TMC207 fumarate, R207910 fumarate) is a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections.
  • Description
    Bedaquiline fumarate (R403323, TMC207 fumarate, R207910 fumarate) is a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections.Bacterial Infection Approved
  • Synonyms
    R403323;TMC207 fumarate;R207910 fumarate
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antibacterial
  • Research Area
    Infection
  • Indication
    Bacterial Infection

Chemical Information

  • CAS Number
    845533-86-0
  • Formula Weight
    671.59
  • Molecular Formula
    C36H35BrN2O6
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 100 mg/mL 148.90 mM; H2O : < 0.1 mg/mL
  • SMILES
    CN(C)CCC(C1=CC=CC2=CC=CC=C21)(C(C3=CC=CC=C3)C4=C(N=C5C=CC(=CC5=C4)Br)OC)O.C(=CC(=O)O)C(=O)O
  • Chemical Name
    (1R,2S)-1-(6-broMo-2-Methoxyquinolin-3-yl)-4-(diMethylaMino)-2-naphthalen-1-yl-1-phenylbutan-2-ol,(E)-but-2-enedioic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Jang JC, et al. J Microbiol. 2017 Apr 20.
2. Pang Y, et al. Antimicrob Agents Chemother. 2017 Apr 24;61(5).
3. Chahine EB, et al. Ann Pharmacother. 2014 Jan;48(1):107-15.
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