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Bedaquiline fumarate

CAS No. 845533-86-0

Bedaquiline fumarate ( R403323;TMC207 fumarate;R207910 fumarate )

Catalog No. M16140 CAS No. 845533-86-0

Bedaquiline fumarate (R403323, TMC207 fumarate, R207910 fumarate) is a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Bedaquiline fumarate
  • Note
    Research use only, not for human use.
  • Brief Description
    Bedaquiline fumarate (R403323, TMC207 fumarate, R207910 fumarate) is a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections.
  • Description
    Bedaquiline fumarate (R403323, TMC207 fumarate, R207910 fumarate) is a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections.Bacterial Infection Approved
  • Synonyms
    R403323;TMC207 fumarate;R207910 fumarate
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antibacterial
  • Research Area
    Infection
  • Indication
    Bacterial Infection

Chemical Information

  • CAS Number
    845533-86-0
  • Formula Weight
    671.59
  • Molecular Formula
    C36H35BrN2O6
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 100 mg/mL 148.90 mM; H2O : < 0.1 mg/mL
  • SMILES
    CN(C)CCC(C1=CC=CC2=CC=CC=C21)(C(C3=CC=CC=C3)C4=C(N=C5C=CC(=CC5=C4)Br)OC)O.C(=CC(=O)O)C(=O)O
  • Chemical Name
    (1R,2S)-1-(6-broMo-2-Methoxyquinolin-3-yl)-4-(diMethylaMino)-2-naphthalen-1-yl-1-phenylbutan-2-ol,(E)-but-2-enedioic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Jang JC, et al. J Microbiol. 2017 Apr 20.
2. Pang Y, et al. Antimicrob Agents Chemother. 2017 Apr 24;61(5).
3. Chahine EB, et al. Ann Pharmacother. 2014 Jan;48(1):107-15.
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